CIST 2019 calls for innovative ideas on the transformational power of information technology, artificial intelligence, and machine learning on individual behavior, business strategies, and society. We invite original research in all areas of Information Systems and related fields that seek to address issues related to the conference theme. The CIST 2019 co-chairs are Ming Fan, Shawndra Hill, Sam Ransbotham, Raghu Santanam, Vilma Todri, and Han Zhang. The submission process will open on May 27th, 2019 and will close on June 16th, 2019. All submissions will be accepted electronically via Conferency. Submission instructions and other conference related information will be posted on the conference website at http://cist2019.conferency.com.